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Concept Discussion: How Directed Evolution will Save the World

Introduction In my previous posts, I have talked about ways of using different microorganisms to produce different things that are of use to humans. Two specific examples were diesel from fungi, or oils from algae. There are many other examples, some of which I hope to cover in my future posts. At the current time, the main challenge to many of these by-products is that they are not produced at efficiencies and quantities that allow for economical use. So how would you make fungi produce more biodiesel? How would you make the breakdown of cellulose happen faster? How do you increase oil production in algae? Although each of these questions, involves a deep understanding of complex cellular networks, at the base of each of these problems is a protein that carries out a given task. Increasing efficiencies of these proteins can help to increase the yields of the desire products. Today, we will look at one way, how proteins can be "engineered" by asking: What is Directe...

Phosphorus

The fact that our overreliance on fossil fuels is quickly draining easily accessible resources is becoming more known in the public. Now there is talk on several scientific and environmental radio shows that warn of declining phosphorus reserves. The concern over a possible phosphorus shortage may seem contradictory to observations of increased algal blooms and eutrophication of inner water streams – a phenomenon where increased chemical nutrients in the environment lead to algal blooms and suffocation of aquatic life with detrimental  consequences to the environment – which at least in part are caused by increased bio-available phosphorus. All this lead me to the question: Is there really a phosphorus shortage? Phosphorus is the 15th element on our periodic table. In nature phosphorus never exists in its elementary form due to its reactivity [1]. Phosphorus is one of the essential elements of life because it is part of many structures in living cells from simple bacteria to c...

Journal Club:" Correlation of cellulase gene expression and cellulolytic acticity throughout the gut of the termite Reticulitermes flavipes."

It has been a while since the last contribution to this site. Today’s blog entry shall be a summary of a journal article that a couple of friends and I started recently to educate ourselves on topics related to bio-based ideas that are of interest to us. Recently, I came across a general article in the Scientist that talked about biofuels production. The article mentioned integrated biofuel productionpipelines that could include the breakdown of agricultural waste products containing cellulose . Cellulose is a complex sugar, meaning that it consists of long-chains of individual simple sugar units such as glucose . The glucose that is released from the breakdown of cellulose could be used for bioethanol production. But it turns out that cellulose is a very sturdy material that is difficult and energy intensive to break down. One way to reduce the cost of break-down would be to rely on enzymes that are known as biological catalysts. Catalysts can reduce the activation energy which is ...

News Flash: 30% Efficient Solar Power Silicon and Nitrite

As reported by Greentechmedia on September 28th, Phoenix-based Rosestreet Labs Energy (RSLE) has successfully tested a new prototype of solar panels able to convert between 25-30% of sunlight into electricity. For comparison, the current maximum for conventional silicon-based solar panel is produced by SunPower can convert around 22.5% of sunlight into electricity. So the increases by RSLE represent a quantum leap in efficiency increases. The efficiency gains come at a cost of increased production costs. RSLE aims to lower production cost to below $ 1.50 per Watt by 2014 which is a goal already achieved by some solar panel manufacturers today. RSLE claims to achieve this feat by combining silicon-based solar technology with other nitride-based alloys - in this case indium and gallium. The combination of silicon and indium and gallium nitride can make use of a broader spectrum of the visible light resulting in higher efficiencies. According to a 2005 press release , unlike conventi...

Of Diatoms, Titanium Dioxide and A Bio-based Way to Increase Solar Power Efficiencies

Prolog: It has been a while since last I discussed a scientific journal paper. The following post is based on a paper published in the American Chemical Society NANO Journal (Vol.2, No. 10, pp 2103-2112) with the title “Metabolic Insertion of Nanostructured TiO2 into the Patterned Biosilica of the Diatom Pinnulario sp. by a Two-Stage Bioreactor Culvtivation Process”. What have they done? The Rorrer lab is a nanotechnology/biotechnology engineering lab. They manipulate various microorganisms so that the microorganisms produce substances that are of use to human kind. Their latest series of publications has focused on diatoms which are single-celled algae that are able to make silica shells with very intricate patterns (see below). The Rorrer lab has a significant body of work inducing a particular diatom by the name of Pinnulario sp . to incorporate optoelectronic substances into its frustules (outer shells) that it normally would not. Optoelectronic substances can transform, tra...

Focus on Algae - Part II: Energy

In the last focus section , we discussed how algae can be used to treat waste waters and mitigate CO2 in the process. Today's post will explore how algae can be used for energy generation. As already mentioned in the last time, biofuels have become very visible as of late due to environmental, economical and geopolitcal reasons. If at the heart of traditional biofuel generation lies in the creation and decomposition of biomass, then it would be easy to substitute corn or other less controversial land-based plants with algae. Although a lot of attention is paid to the use of algae in biofuel generation, and this article also mainly focusses on this aspect, it should be noted that algae can also be used to generate electricity by direct combustion of the biomass. Plans for these kinds of schemes are already on the way in Venice and a few other European locations [1]. Algae and Biofuels What happens to the biomass after it has been created depends on the type of biofuel that is de...

What are Biofuels?

Introduction With prices for crude oil spiking in the recent past, and an unstable Middle East and intensifying effects of climate disruptions, the Obama administration and governments around the world have been promoting the development, and deployment of newer, more sustainable forms of energy generation, amongst which are biofuels . What are Biofuels? At the heart of every hydrocarbon based fuel (gasoline, diesel, kerosene, coal) are anaerobic degradation processes of organic material. For fossil fuels , the source of organic material comes from planctonic life, plants, and animals that lived and died millions of years ago. For biofuels, the source of organic material comes from planctonic life, plants or other sources of much more recent origin. The important concepts to note are: 1.) Building up organic matter removes carbon dioxide from the atmosphere. 2.) Burning hydrocarbon based fuels releases the carbon originally tied up in the form of carbon dioxide. So when we pump up t...